Phytochemical Screening And Activity Test of Maja Fruit Extract (Aegle Marmelos L.) on Growth Salmonella typhi and Vibrio cholerae
DOI:
https://doi.org/10.56711/jms.v3i2.974Abstract
Maja fruit (Aegle marmelos L.) contains secondary metabolites that have antibacterial activity in the form of steroids, flavonoids and saponins, which are not used optimally. The target of this study was to observe the antibacterial activity of Maja fruit (Aegle armelos L.) extract on Vibrio cholera and Salmonella typhi. The extraction method formed by maceration and using 96% ethanol solution then the antibacterial activity was tested on the agar diffusion technique. The results of the study show that the range of inhibition zone diameter (mm) is gradual for the Maja Fruit (Aegle marmelos L.) extract test at concentrations of 2%, 4%, 8%. For Salmonella typhi was 13 mm;16,3 mm;19 mm but ciprofloxacin as a positive control was 57mm and DMSO as a negative control did not show any inhibition zone. However, the diameter of the inhibition zone in Vibrio cholera was found to be in the range of 13 mm;18.3 mm;19.6 mm and the positive control ciprofloxacin was 32.3 mm , but the negative control did not have an inhibiting zone. The results of statistical tests showed that Maja fruit (Aegle marmelos L.) extract had antibacterial activity on Vibrio cholerae and Salmonella typhi at the maximum concentration of 2% w/v (P <0.05).
References
Zulita Z., Rani, R., Aulia, M., & Nurhadini. (2018). Uji Aktivitas Antibakteri Ekstrak Daun Karamunting (Rhodomyrtus Tomentosa) terhadap Bakteri Staphylococcus aureus dan Shigella sp. Prosiding Seminar Nasional Penelitian & Pengabdian pada Masyarakat: Pangkal Pinang. https://journal.ubb.ac.id/snppm/article/view/618%0Ahttps://journal.ubb.ac.id/snppm/article/download/618/553
Wahyuni, R. A., Putri, I. Y., Jayadi, E. L., & Prastiyanto, M. E. (2019). Antibacterial Activity Of Parijoto Fruit Extract (Medinilla Speciosa) On Bacteria Extended Spectrum Betalactamase (Esbl) Escherichia Coli And Methicillin Resistant Staphylococcus Aureus (Mrsa). Jurnal Media Analis Kesehatan, 10(2), 106. Https://Doi.Org/10.32382/Mak.V10i2.1250
Agustina, E. (2017). Uji Aktivitas Senyawa Antioksidan dari Ekstrak Daun Tiin (Ficus carica L.) dengan Pelarut Air, Metanol dan Campuran Metanol-Air. Klorofil, 1(1), 38–47. http://dx.doi.org/10.30821/kfl:jibt.v1i1.1240.
Wilujeng S, Kristianto S, Isrianto PL. Pemanfaatan Tanaman Maja (Aegle Marmelos (L.) Correa) Sebagai Upaya Meningkatkan Stamina Pada Masa Pandemi Covid-19 Di Desa Mulyoagung, Dau, Malang. Mitra Mahajana: Jurnal Pengabdian Masyarakat. 2022; 3(1):80–88
Patil, D. N., Kulkarni, A. R., & Patil, B. S. (2010). Fruit Gum of Aegle marmelos As Pharmaceutical Aid. International Journal Of Pharmacology. 6(1):68-71. https://doi.org/10.3923/IJP.2010.68.71
Badaring, D. R., Sari, S. P. M., Nurhabiba, S., Wulan, W., & Lembang, S. A. R. (2020). Uji Ekstrak Daun Maja (Aegle marmelos L.) terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Indonesian Journal of Fundamental Sciences, 6(1), 16. https://doi.org/10.26858/ijfs.v6i1.13941
kemenkes RI. Formularies. Pocket Handbook of Nonhuman Primate Clinical Medicine. 2017; :213–218
Ratnah St dan Alfrida Salasa. (2019). Formulasi Sabun Cair Ekstrak Daun Kecombrang sebagai Antikeputihan. Jurnal Media Farmasi, 15(3). https://doi.org/10.32382/mf.v15i2.1125
Harbone, J.B. (2006). Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan. Edisi Kedua. Institut Tehnik Bandung: Bandung
Salasa, A. M., Sapitri, D. N., Lestari, T. R., Asyirah, A. N. (2018). Aktivitas Antibakteri Rebusan Kulit Buah Manggis (Garcinia mangostana L.) Terhadap Pertumbuhan Staphylococcus aureus dan Salmonella thypi. Jurnal Media Farmasi, 14(1): 93-96. https://doi.org/10.32382/mf.v14i1.79
Riwanti, P., Izazih, F., & Amaliyah, A. (2018). Pengaruh Perbedaan Konsentrasi Etanol pada Kadar Flavonoid Total Ekstrak Etanol 50,70 dan 96% Sargassum polycystum dari Madura. Journal of Pharmaceutical-Care Anwar Medika, 2(2), 35–48. https://doi.org/10.36932/jpcam.v2i2.1
Amelinda, E., Widarta, I. W. R., & Darmayanti, L. P. T. (2018). Pengaruh Waktu Maserasi Terhadap Aktivitas Antioksidan Ekstrak Rimpang Temulawak (Curcuma xanthorriza Roxb.). Jurnal Ilmu Dan Teknologi Pangan (ITEPA), 7(4), 165. https://doi.org/10.24843/itepa.2018.v07.i04.p03
Fauzi, M. N. (2021). Ekstraksi dan Uji kandungan Antioksidan buah maja (Aegle Marmelos (L.)Corr ) dengan metode Spektrofotometri UV-VIS. 1996, 6. http://eprints.poltektegal.ac.id/93/1/Ekstrasi Dan Uji Kandungan Antioksidan Buah Maja.pdf.
Riwanti, P., & Izazih, F. (2019). Skrining Fitokimia Ekstrak Etanol 96% Sargassum polycystum dan Profile dengan Spektrofotometri Infrared. Acta Holistica Pharmaciana, 2(1), 34–41
Saptowo, A., Supriningrum, R., & dan Supomo. (2022). Uji Aktivitas Antibakteri Ekstrak Kulit Sekilang ( Embeliaborneensis Scheff ) Terhadap Bakteri Propionibacterium acnes dan Staphylococcus epidermidis. Jurnal Akualtur Rawa Indonesia. 93–97. https://ejournal.unsri.ac.id/index.php/jari/article/download/18678/7347
Anggraini, W., Nisa, S. C., Da, R. R., & Ma, B. (2019). Aktivitas Antibakteri Ekstrak Etanol 96 % Buah Blewah terhadap Eschericia coli Pharmaceutical Journal of Indonesia, 5(1), 61–66
Downloads
Published
Issue
Section
License
OPEN ACCESS POLICY
The Journal Microbiology Science (JMS) is an open access journal, with the aim of informing and publishing research results for development of science and technology, especially in the field of microbiology freely available to the public supports a greater global exchange of knowledge. All articles can be downloaded for free. Articles published in the Journal are Open Access articles distributed under Creative Commons Attribution-ShareAlike 4.0 International License.
The benefits of open access for authors include:
- Open access articles are freely available online and permanently.
- Authors hold copyright to their work..
- Increased visibility and readership.
- No spatial restrictions.
For readers to become writers, There is no space limit for additional material including images, extensive data, or video recordings. Allows readers to read, downloads, quotes, distributes, prints, searches, or links to the full text and allows readers to use them for other lawful purposes.
COPYRIGHT
Submission of a manuscript implies that the submitted work has not been published before (except as part of a thesis, report, or abstract), is not under consideration for publication elsewhere, and has been approved by all co-authors. Upon acceptance, authors retain copyright to their work and grant the Journal Microbiology Science (JMS) a license to distribute the work under the Creative Commons Attribution-ShareAlike 4.0 International License. This license permits others to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material for any purpose, including commercial use), provided proper credit is given to the original authors, changes are indicated, and any derivative works are distributed under the same license. Authors are encouraged to manage intellectual property rights, including patents, for any new inventions prior to publication.
DISCLAIMER
No responsibility is assumed by publisher and co-publishers, nor by the editors for any injury and/or damage to persons or property as a result of any actual or alleged libelous statements, infringement of intellectual property or privacy rights, or products liability, whether resulting from negligence or otherwise, or from any use or operation of any ideas, instructions, procedures, products or methods contained in the material therein

Journal Microbiology Science by Faculty of Pharmacy Universitas Muslim Indonesia is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
