Phytochemical Screening And Activity Test of Maja Fruit Extract (Aegle Marmelos L.) on Growth Salmonella typhi and Vibrio cholerae

Nur Annah Achriana Yusuf, St. Rannah, Alfrida Monica Salasa

Sari


Maja fruit (Aegle marmelos L.) contains secondary metabolites that have antibacterial activity in the form of steroids, flavonoids and saponins, which are not used optimally. The target of this study was to observe the antibacterial activity of Maja fruit (Aegle armelos L.) extract on Vibrio cholera and Salmonella typhi. The extraction method formed by maceration and using 96% ethanol solution then the antibacterial activity was tested on the agar diffusion technique. The results of the study show that the range of inhibition zone diameter (mm) is gradual for the Maja Fruit (Aegle marmelos L.) extract test at concentrations of 2%, 4%, 8%. For Salmonella typhi was 13 mm;16,3 mm;19 mm but ciprofloxacin as a positive control was 57mm and DMSO as a negative control did not show any inhibition zone. However, the diameter of the inhibition zone in Vibrio cholera was found to be in the range of 13 mm;18.3 mm;19.6 mm and the positive control ciprofloxacin was 32.3 mm , but the negative control did not have an inhibiting zone. The results of statistical tests showed that Maja fruit (Aegle marmelos L.)  extract had antibacterial activity on Vibrio cholerae and Salmonella typhi at the maximum concentration of 2% w/v (P <0.05).


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Zulita Z., Rani, R., Aulia, M., & Nurhadini. (2018). Uji Aktivitas Antibakteri Ekstrak Daun Karamunting (Rhodomyrtus Tomentosa) terhadap Bakteri Staphylococcus aureus dan Shigella sp. Prosiding Seminar Nasional Penelitian & Pengabdian pada Masyarakat: Pangkal Pinang. https://journal.ubb.ac.id/snppm/article/view/618%0Ahttps://journal.ubb.ac.id/snppm/article/download/618/553

Wahyuni, R. A., Putri, I. Y., Jayadi, E. L., & Prastiyanto, M. E. (2019). Antibacterial Activity Of Parijoto Fruit Extract (Medinilla Speciosa) On Bacteria Extended Spectrum Betalactamase (Esbl) Escherichia Coli And Methicillin Resistant Staphylococcus Aureus (Mrsa). Jurnal Media Analis Kesehatan, 10(2), 106. Https://Doi.Org/10.32382/Mak.V10i2.1250

Agustina, E. (2017). Uji Aktivitas Senyawa Antioksidan dari Ekstrak Daun Tiin (Ficus carica L.) dengan Pelarut Air, Metanol dan Campuran Metanol-Air. Klorofil, 1(1), 38–47. http://dx.doi.org/10.30821/kfl:jibt.v1i1.1240.

Wilujeng S, Kristianto S, Isrianto PL. Pemanfaatan Tanaman Maja (Aegle Marmelos (L.) Correa) Sebagai Upaya Meningkatkan Stamina Pada Masa Pandemi Covid-19 Di Desa Mulyoagung, Dau, Malang. Mitra Mahajana: Jurnal Pengabdian Masyarakat. 2022; 3(1):80–88

Patil, D. N., Kulkarni, A. R., & Patil, B. S. (2010). Fruit Gum of Aegle marmelos As Pharmaceutical Aid. International Journal Of Pharmacology. 6(1):68-71. https://doi.org/10.3923/IJP.2010.68.71

Badaring, D. R., Sari, S. P. M., Nurhabiba, S., Wulan, W., & Lembang, S. A. R. (2020). Uji Ekstrak Daun Maja (Aegle marmelos L.) terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Indonesian Journal of Fundamental Sciences, 6(1), 16. https://doi.org/10.26858/ijfs.v6i1.13941

kemenkes RI. Formularies. Pocket Handbook of Nonhuman Primate Clinical Medicine. 2017; :213–218

Ratnah St dan Alfrida Salasa. (2019). Formulasi Sabun Cair Ekstrak Daun Kecombrang sebagai Antikeputihan. Jurnal Media Farmasi, 15(3). https://doi.org/10.32382/mf.v15i2.1125

Harbone, J.B. (2006). Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan. Edisi Kedua. Institut Tehnik Bandung: Bandung

Salasa, A. M., Sapitri, D. N., Lestari, T. R., Asyirah, A. N. (2018). Aktivitas Antibakteri Rebusan Kulit Buah Manggis (Garcinia mangostana L.) Terhadap Pertumbuhan Staphylococcus aureus dan Salmonella thypi. Jurnal Media Farmasi, 14(1): 93-96. https://doi.org/10.32382/mf.v14i1.79

Riwanti, P., Izazih, F., & Amaliyah, A. (2018). Pengaruh Perbedaan Konsentrasi Etanol pada Kadar Flavonoid Total Ekstrak Etanol 50,70 dan 96% Sargassum polycystum dari Madura. Journal of Pharmaceutical-Care Anwar Medika, 2(2), 35–48. https://doi.org/10.36932/jpcam.v2i2.1

Amelinda, E., Widarta, I. W. R., & Darmayanti, L. P. T. (2018). Pengaruh Waktu Maserasi Terhadap Aktivitas Antioksidan Ekstrak Rimpang Temulawak (Curcuma xanthorriza Roxb.). Jurnal Ilmu Dan Teknologi Pangan (ITEPA), 7(4), 165. https://doi.org/10.24843/itepa.2018.v07.i04.p03

Fauzi, M. N. (2021). Ekstraksi dan Uji kandungan Antioksidan buah maja (Aegle Marmelos (L.)Corr ) dengan metode Spektrofotometri UV-VIS. 1996, 6. http://eprints.poltektegal.ac.id/93/1/Ekstrasi Dan Uji Kandungan Antioksidan Buah Maja.pdf.

Riwanti, P., & Izazih, F. (2019). Skrining Fitokimia Ekstrak Etanol 96% Sargassum polycystum dan Profile dengan Spektrofotometri Infrared. Acta Holistica Pharmaciana, 2(1), 34–41

Saptowo, A., Supriningrum, R., & dan Supomo. (2022). Uji Aktivitas Antibakteri Ekstrak Kulit Sekilang ( Embeliaborneensis Scheff ) Terhadap Bakteri Propionibacterium acnes dan Staphylococcus epidermidis. Jurnal Akualtur Rawa Indonesia. 93–97. https://ejournal.unsri.ac.id/index.php/jari/article/download/18678/7347

Anggraini, W., Nisa, S. C., Da, R. R., & Ma, B. (2019). Aktivitas Antibakteri Ekstrak Etanol 96 % Buah Blewah terhadap Eschericia coli Pharmaceutical Journal of Indonesia, 5(1), 61–66




DOI: https://doi.org/10.56711/jms.v3i2.974

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