Antibacterial Activity of Endophytic Fungi Isolated from Parang Romang (Boehmeria virgata (G.Forst) Guill) Leaves Against Gastrointestinal Pathogens

Rusli Rusli, Ayyub Harly Nurung, Muh. Ivan Sandyna

Sari


Parang romang (Boehmeria virgata (G.Forst) Guill) is a plant traditionally used for treating various digestive tract infections. However, obtaining bioactive compounds directly from the plant requires significant biomass. Therefore, endophytic fungi, sourced from specific plant parts, are explored for their ability to produce similar bioactive compounds. The research examined the potential antibacterial activity of endophytic fungi isolated from parang romang leaves against common gastrointestinal pathogens. The methods used in was, characterization of endophytic fungal isolates, and antagonistic activity was evaluated using the agar diffusion method. The results showed that the endophytic fungal strains, namely isolates IFBV 6, IFBV 7, and IFBV 10 could inhibit the bacteria Escherichia coli, Salmonella typhi, Shigella dysenteriae, and Vibrio cholera. With an average zone of inhibition for each strains isolate against Esherichia coli respectively 11.53 mm, 10.49 mm, and 14.85 mm; Salmonella typhi 14.47 mm, 8.66 mm, and 15.51 mm; Shigella dysenteriae 22.28 mm, 13.76 mm, and 15.33 mm; and Vibrio cholera 16.91mm, 11.94mm, 15.16mm. In conclusion, isolated endophytic fungal strains hold promise as potential as antibacterialn agents.

Teks Lengkap:

PDF

Referensi


Astuti AT et al. Penyakit Infeksi Dalam Kehamilan Dan Nifas. Padang: Get Press. 2023

Ulfah Cahyameta Siswoyo, Sri Peni Fitrianingsih, Siti Hazar. Studi Literatur Potensi Antibakteri Tanaman Sawo (Manilkara Zapota (L.) P. Royen) Terhadap Bakteri Penyebab Infeksi Saluran Pencernaan. Bandung Conf Ser Pharm.; 2(2). DOI: 10.29313/bcsp.v2i2.4111

Darmadi. Infeksi Nosokomial: Problematika Dan Pengendaliannya. Jakarta: Penerbit Salemba Medika. 2008

Kementrian Kesehatan Republik Indonesia. Profil Kesehatan Indonesia 2021. Jakarta: Kementrian Kesehatan Republik Indonesia. 2022

Hauser AR. Antibiotic Basics For Clinicians: The ABCs of Choosing The Right Antibacterial Agent. 2nd ed. Philladephia: Lippincot Williams & Wilkins. 2013

Perdana AT et al. Penyakit Infeksi. Padang: Global Eksekutif Teknologi. 2023

Suprayitno E et al. Biokimia Produk Prikanan. Malang: UB Press. 2021

Tarigan IL, Latief M. Antibakteri: Potensi Tanaman Jambi. Tasikmalaya: Edupublisher. 2021

Cambie R., Ash J. Fijian Medicinal Plants. Australia: CSIRO Publishing. 1994

Muslimin L et al. Anti-Proliferation Activity of Nanoencapsulated Bioadhesive Vaginal Gel of Isolated Active Compound (BVI03) From Boehmeria Virgata (Forst) Guill Leaves Against Human Cancer Cervix Hela Cells. Int J Pharma Sci Res. 2015; 6(5):836–839

Rusdi M. Skrining Fitokimia Dan Uji Toksisitas Ekstrak Akar Parang Romang (Boehmeria Virgata (Forst) Guill) Terhadap Larva Udang Artemia Salina Leach. FARBAL. 2014

Manggau M et al. In Vitro Study of the Alkaloid Anticancer Compound From Makassar Medicinal Plants Boehmeria virgata Linn. Int J Phatmaceutical Sci Rev Res. 2018; 49(1):77–81

Rusdi M, Hasrina, Noer SF, Bariun H. Uji Efek Hipoglikemik Ekstrak Etanol Akar Parang Romang (Boehmeria virgata (Forst) Guill) Terhadap Mencit Jantan. FARBAL. 2016; 4(1):33–36

Rusdi M, Ikhlas M, Kartikasari NP. Antituberculosis Activity of Parang Romang (Boehmeria virgata (Forst.) Guill) Stem Extract. ad-Dawaa’ J Pharm Sci.; 4(1). DOI: 10.24252/djps.v4i1.21359

Lukman M, Christin V. Analisis Profil Bobot Badan Tikus Dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus). J Farm Galen (Galenika J Pharmacy). 2020; 6(1):1–6

Faulina Putri M, Fifendy M, Hilda Putri D. Diversitas Bakteri Endofit Pada Daun Muda Dan Tua Tumbuhan Andaleh (Morus macroura Miq.). EKSAKTA. 2018; 19(1):126–130

Rollando. Senyawa Antibakteri Dari Fungi Endofit. Malang. 2019

Rori CA, Kandou F.E F, Tangapo AM. Aktivitas Enzim Ekstraseluler Dari Bakteri Endofit Tumbuhan Mangrove Avicennia marina. J Bios Logos. 2020; 10(2):48–55

Cahaya N, Ibrahim A, Ramadhan AM, Rusli. Isolasi Jamur Endofit Daun Jahe Merah (Zingiber officinale). Pros Semin Nas Kefarmasian. 2016; 4:227–231

Tylova VN, Bahri S, Juanda BR, Kusdiana APJ. Eksplorasi Bakteri Endofit Terhadap Cendawan Pestalotiopsis Microspora Penyebab Penyakit Gugur Daun Pada Tanaman Karet (Hevea brasiliensis Muell. Arg.). J Ilmu-Ilmu Pertan Indones. 2023; 25(1):51–58

Shofiana RH, Sulistyowati L, Muhibuddin A. Eksplorasi Jamur Endofit Dan Khamir Pada Tanaman Cengkeh (Syzygium aromaticum) Serta Uji Potensi Antagonismenya Terhadap Jamur Akar Putih (Rigidoporus microporus). Hpt. 2015; 3(1):75–83

Rosyadi A, Triatmoko B, Nugraha AS. Isolation of Estuary Soil Fungi and Screening Antibacterial Activity Against Staphylococcus aureus. Indones J Pharm Sci Technol. 2022; 9(1):17–25

Rofika E, Fitriana F, Herwin H. Identification Of Endopytic Fungi Compound On White Weed Leaves (Ageratum conyzoides L.) Containing The Potential To Produce Antiviotics By TLC-Bioautography. J Microbiol Sci. 2023; 3(1):13–23

Datta FU et al. Uji Aktivitas Antimikroba Bakteri Asam Laktat Cairan Rumen Terhadap Pertumbuhan Salmonella enteritidis, Bacillus cereus, Escherichia coli Dan Staphylococcus aureus Menggunakan Metode Difusi Sumur Agar. e-Journal Undana. 2019; 66–85




DOI: https://doi.org/10.56711/jms.v4i2.1081

Refbacks

  • Saat ini tidak ada refbacks.


##submission.copyrightStatement##

Indexed by:

     


ISSN: 2808-392X | e-ISSN: 2808-3911

Editor's Address:

3rd Floor Laboratory Faculty of Pharmacy,
2nd Campus of UMI: Jl. Urip Sumoharjo km. 5 , Makassar, South Sulawesi, Indonesia

Phone: +62 821 89555447
Fax: +62411425619
E-mail: jmic.sci@umi.ac.id