Drying Temperature Modulates Antioxidant Activity of Bitter Melon (Momordica charantia L .)

Widyawati Widyawati, A. Muflihunna, Rahmawati Rahmawati, Faradiba Abdul Rasyid, Dewi Yuliana, Rezki Amriati Syarif

Abstract


Bitter melon (Momordica charantia L.) is recognized for its antioxidant-rich bioactive compounds, notably flavonoids and polyphenols. Thermal processing may compromise these compounds, affecting antioxidant capacity. This study evaluated the influence of drying temperature on the antioxidant activity of bitter melon fruit using the DPPH assay. Samples were dried at room temperature and 50 ℃, with activity assessed by absorbance at 518 nm and IC₅₀ calculation. Results demonstrated higher antioxidant activity at room temperature (IC₅₀ = 20.631 µg/mL) than samples dried at 50 ℃ (IC₅₀ = 44.390 µg/mL). These findings highlight that elevated drying temperatures reduce the radical scavenging potential of M. charantia, emphasizing the role of processing conditions in maintaining its functional quality.

Keywords


Momordica charantia; Bitter Melon; antioxidant; DPPH; drying temperature

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References


Aminah., Maryam, S., Baits, M & Kalsum, U. (2016) “Perbandingan Aktivitas Antioksidan Ekstrak Etanol Daun Sirsak (Annona muricata L.) Berdasarkan Tempat Tumbuh Dengan Metode Perendaman DPPH,” Jurnal Fitofarmaka Indonesia, 3(1), pp. 146–150.

Artati., Widarti., Hasan, Z.A & Askar, M. (2024) “Aktivitas Antioksidan Dari Tiga Fraksi Pelarut Ekstrak Daun Dandang Gendis (EDDG),” Jurnal Media Analis Kesehatan, 15(2), pp. 132–139. https://ojs3.poltekkesmks.ac.id/index.php/medankes.

Belgur, F., Indrawati, M. and Duly, F. (2021) “Uji Aktivitas Antioksidan Ekstrak Etanol Buah Pare (Momordica Charantia L.) Dengan Metode DPPH (1,1-diphenyl-2-picrilhydrazil),” Jurnal FarmasiKoe, 4(2), pp. 1–5. http://jurnal.poltekeskupang.ac.id/index.php/koe.

Hasanah, N. and Novian, D.R. (2020) “Analisis Ekstrak Etanol Buah Labu Kuning (Cucurbita Moschata D.),” Jurnal Ilmiah Farmasi, 9(1), pp. 54–59. http://ejournal.poltektegal.ac.id/index.php/parapemikir.

Luliana, S., Purwanti, N.U. & Manihuruk, K.N. (2016) “Pengaruh Cara Pengeringan Simplisia Daun Senggani (Melastoma malabathricum L.) Terhadap Aktivitas Antioksidan Menggunakan Metode DPPH (2,2-difenil-1-pikrilhidrazil),” Pharmaceutical Sciences and Research, 3(3), pp. 120–129.

Marbun, R.R.M., Sholahuddin, S. & Rahayuni, T. (2020) “Pengarub Kombinasi Suhu dan Dehumidifikasi Udara Pengeringan Terhadap Aktivitas Antioksidan Irisan Buah Mengkudu (Morinda citrifolia),” Jurnal Ilmu dan Teknologi Pangan, 6(1), pp. 560–567. http://www.profood.unram.ac.id/index.php/profood.

Rikantara, F.S., Utami, M.R. & Kasasiah, A. (2022) “Aktivitas Antioksidan Kombinasi Ekstrak Daun Sirsak (Annona muricata L.) dan Ekstrak Daun Pepaya (Carica papaya L.) dengan Metode DPPH,” Lumbung Farmasi: Jurnal Ilmu Kefarmasian, 3(2), pp. 124–133. http://journal.ummat.ac.id/index.php/farmasi/article/view/8819.

Sakka, L. & Muin, R. (2022) “Identifikasi Kandungan Senyawa Antioksidan Ekstrak Daun Bidara (Ziziphus mauritiana Lamk.) Dengan Menggunakan Metode DPPH,” Journal Syifa Sciences and Clinical Research, 4(1), pp. 92–100. http://ejurnal.ung.ac.id/index.php/jsscr.

Salsabillah, C., Abdullah, A. & Nur, A. (2025) “Pengaruh Suhu Pengeringan terhadap Aktivitas Antioksidan Ekstrak Daun Ungu (Graptophyllum pictum L. Griff),” Jurnal Pharmascience, 12(1), pp. 157. http://dx.doi.org/10.20527/jps.v12i1.21010.

Septiningsih, R., Sutanto, S. & Indriani, D. (2017) “Aktivitas Antioksidan Ekstrak Etanol Daun, Buah dan Biji Pare (Momordica charantina L),” FITOFARMAKA: Jurnal Ilmiah Farmasi, 7(1), pp. 4–12.

Syafiqah, A.R. & Damanhuri (2023) “Uji Daya Hasil Dua Galur Harapan Tanaman Paria ( Momordica charantia L .) di Dataran Medium,” 11(1), pp. 56–62. http://dx.doi.org/10.21776/ub.protan.2023.011.01.06.

Widyasanti, A., Nurlaily, N. & Wulandari, E. (2018) “Karakteristik Fisikokimia Antosianin Ekstra Kulit Buah Naga Merah Menggunakan Metode UAE," Jurnal Ilmiah Rekayasa Pertanian dan Biosistem, 6(1), pp. 27–38. https://doi.org/10.29303/jrpb.v6i1.63.




DOI: https://doi.org/10.33096/jffi.v12i3.1388

Copyright (c) 2025 Widyawati Widyawati, A. Muflihunna, Rahmawati Rahmawati, Faradiba Abdul Rasyid, Dewi Yuliana, Rezki Amriati Syarif

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