EVALUASI STABILITAS FARMASETIK DAN UJI IRITASI FORMULA MASKER SARI LEMON (Citrus limon L.) DENGAN YOGURT PLAIN

Iskandar Zulkarnain, Ermina Pakki, Mirawati Mirawati, Arin Rizki Talib

Sari


The use of lemon juice and yogurt can provide good care for facial skin, so have the potential to be formulated into a mask to overcome skin problems. The study aimed to produce a mask dosage froms formula pharmaceutically stable and not irritating. The lemon juice extract was obtained by using freeze-drying, and optimization of anionic emulgator (TEA-Stearate) and nonionic emulgator (Tween-Span 60) are carried out. The formulation was continued with the variations in lemon extract concentrations of 0.5; 1; and 2% w/v by evaluating the physical characteristics and stability with parameters including organoleptic examination (smell, color, and consistency), centrifugation, homogeneity, pH, type of emulsion, drying time, dispersion, viscosity, and determination of flow type before and after conditions are forced at 5oC and 35oC for the 10 cycles for irritation testing using test rabbits. The results showed that the formula with an anionic emulgator (TEA-stearic) of 1:2% b/v with a lemon extract concentration of 1% was a pharmaceutically stable formula and the irritation the results showed that the formula with a lemon extract of 0.5% and 1% b/v did not cause any irritation.

Kata Kunci


Lemon juice, Citrus limonL., Yought Plain, Cream mask, Irritation.

Teks Lengkap:

Fulltext PDF

Referensi


Maregesi SM, Kagashe GA, Felix F. Documentation and Phytochemical Screening of Traditional Beauty Products Used in Missenyi District of Tanzania. Journal of Cosmetics Dermatological Sciences and Applications. 2014;4:360.

Atsmanul A. Aktivitas Protease dan Kandungan Asam Laktat pada Yoghurt yang Dimodifikasi Bifidobacterium bifidum dan Diinokulasi Pseudomonas fluorescens (Skripsi). Bogor: Fakultas Matematika dan Ilmu Pengetahuan Alam. Universitas Institus Pertanian Bogor, 2006.

Thanya P. Development of Herbal Facial Mask Cream From Suan Sunandha Palace Facial. International Journal of Advances in Science Engineering and Technology. 2017;5(1):23.

Surtiningsih. Cantik dengan Bahan Alami. Jakarta: PT.Alex Media Komputindo, 2005.

Rohana. Pengaplikasikan Masker Ekstrak Essensial Oil Mawar Pada Jenis Kulit Kering Untuk Usia Setengah Baya. Jurnal Keluarga Sehat Sejahtera.2014;12:26.

Ariyani B. Formulasi Krim Masker Wajah Menggunakan Lapisan Putih Kulit Semangka (Citrullus vulgaris Schard) Sebagai Pelembab. Jurnal Media Farmasi. 2013;11(18):37-38.

Faradiba A, Faisal M, Ruhama. Formulasi Krim Wajah Dari Sari Buah Jeruk Lemon (Citrus lemon L.) dan Anggur Merah (Vitisvinifera L.) dengan variasi konsentrasi emulgator. Jurnal farmasi dan farmakologi. 2013;17(1):17-18.

Lachman L, Lieberman AH, Kanig L. Teoridan Praktek Farmasi Industri, Edisi ke 3. Jakarta: Penerbit Universitas Indonesia, 1994.

Aisyah F. Uji Iritasi Krim Hasil Fermentasi Bunga Rosella (Hibiscus sabdariffa L.) Dengan Variasi Konsentrasi Emulgator Novemer Pada Kulit Kelinci (Oryctalagus cuniculus). Journal of Pharmaceutical and Medicinal Sciences. 2016;1(2):64.

Vieira RP. Physical and Physicochemical Stability Evaluation of Cosmetic Formulations Containing Soybean Extract Fermented by Bifidobacterium animalis. Brazilian Journal of Pharmaceutical Sciences. 200945(3):517.


Refbacks

  • Saat ini tidak ada refbacks.


View My Stats