Phytochemical Screening and α-glucosidase Inhibitory of Secang Wood (Caesalpinia sappan L.)
DOI:
https://doi.org/10.33096/jffi.v10i3.1101Keywords:
Caesalpinia sappan L., acarbose, alphaglucosidase, Inhibitor, ELISA (Enzyme-Linked Immunosorbant Assay) readerAbstract
Secang wood (Caesalpinia sappan L.) is a part of the Secang plant which is widely used to treat various diseases, including diabetes. Based on previous research, secang wood contains flavonoids which have the potential to inhibit the α-glucosidase enzyme. The research aims to determine the potential of ethanol extracted by meseration using 96% ethanol. Inhibition of activity was tested using microplate reader which was measured at a wavelength of 405 nm with acarbose as a comparison. The results of the research show that the ethanol extract of secang wood has inhibitory activity, including it in the active category based on the % inhibition value obtained at 83.63%. Meanwhile, acarbose has inhibitory activity, including it in the very active category with a %inhibition value of 79%.References
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