Phytochemical Screening and α-glucosidase Inhibitory of Secang Wood (Caesalpinia sappan L.)

Aktsar Roskiana Ahmad, Tiara Katulista Islamia, Asni Amin

Abstract


Secang wood (Caesalpinia sappan L.) is a part of the Secang plant which is widely used to treat various diseases, including diabetes. Based on previous research, secang wood contains flavonoids which have the potential to inhibit the α-glucosidase enzyme. The research aims to determine the potential of ethanol extracted by meseration using 96% ethanol. Inhibition of activity was tested using microplate reader which was measured at a wavelength of 405 nm with acarbose as a comparison. The results of the research show that the ethanol extract of secang wood has inhibitory activity, including it in the active category based on the % inhibition value obtained at 83.63%. Meanwhile, acarbose has inhibitory activity, including it in the very active category with a %inhibition value of 79%.

Keywords


Caesalpinia sappan L.; acarbose; alphaglucosidase; Inhibitor; ELISA (Enzyme-Linked Immunosorbant Assay) reader

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DOI: https://doi.org/10.33096/jffi.v10i3.1101

Copyright (c) 2023 Tiara Katulista Islamia, Asni Amin, Aktsar Roskiana Ahmad

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ISSN: 2356-0398 | e-ISSN: 2541-2329

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