UJI AKTIVITAS ANTIOKSIDAN ETANOL BUAH TIN (Ficus carica) DENGAN METODE DPPH DAN FRAP
DOI:
https://doi.org/10.56711/jifa.v15i1.976Keywords:
Antioxidants, DPPH, Figs, FRAPAbstract
Indonesia as a developing country has limitations in overcoming health problems. Based on the 2018 National Basic Health Research (Riskesdas), the prevalence of degenerative diseases is increasing. The main cause of death was stroke (15.4%) followed by hypertension, diabetes mellitus, and tumors. One of the causes of this degenerative disease is oxidative stress, namely the large number of oxidants in the body through an oxidation process. Antioxidants are compounds that prevent or postpone oxidation reaction of a molecule by inhibiting initiation or propagation process of the chain oxidation reaction The chemical structure of antioxidants, free radical sources, and physico-chemical properties of different sample preparations can provide various antioxidant activity test results. Therefore, a selective antioxidant activity analysis method is needed for a certain type of sample. The purpose of this study was to test the antioxidant activity of the ethanol extract of fig fruit using the DPPH and FRAP. Methods This research was conducted using the antioxidant activity test method DPPH and FRAP. Based on the research results of antioxidant activity using the DPPH method, the IC50 value of the ethanol extract of fig fruit was 121.74 μg/mL and the FRAP method obtained a value of 11.11 mgAAE/g extractReferences
Kementrian Kesehatan RI. Hasil Utama Riskesdas. Jakarta: Badan Penelitian dan Pengembangan Kesehatan. 2018
Rahmi H. Review: Aktivitas Antioksidan dari Berbagai Sumber Buah-Buahan di Indonesia. Jurnal Agrotek Indonesia (Indonesian Journal of Agrotech). 2017; 2(1):34–38
Winarsi H. Antioksidan Alami Dan Radikal Bebas. Yogyakarta: Kanisus. 2007
Kumalaningsih S. Antioksidan Alami. Surabaya: Trubus Agrisarana. 2006
Sies H, Stahl W. Vitamins E and C, Beta-Carotene, and Other Carotenoids as Antioxidants. Am J Clin Nutr. 1995; 62(6 Suppl):1315–1321
Bouyahya A, Bensaid M, Bakri Y, Dakka N. Phytochemistry and Ethnopharmacology of Ficus carica. Int J Biochem Res Rev. 2016; 14(1):1–12
Ridho E Al. Uji Aktivitas Antioksidan Ekstrak Metanol Buah Lakum (Cayratia trifolia) dengan Metode DPPH (2,2-Difenil-1-Pikrilhidrazil). Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN.; 1(1)
Maryam S, Baits M, Nadia A. Pengukuran Aktivitas Antioksidan Ekstrak Etanol Daun Kelor (Moringa oleifera Lam.) Menggunakan Metode FRAP (Ferric Reducing Antioxidant Power). Jurnal Fitofarmaka Indonesia. 2015; 2(2):115–118
Shah P, Modi HA. Comparative Study of DPPH, ABTS and FRAP Assays for Determination of Antioxidant Activity. In: International Journal for Research in Applied Science & Engineering Technology (IJRASET). 2020, pp. 636–641
Tahir M, Heluth AC, Widiastuti H. Uji Aktivitas Antioksidan Buah Semangka (Citrullus lanatus) Dengan Metode FRAP. As-Syifaa Jurnal Farmasi. 2016; 8(1):31–38
Kim J-S. Radical Scavenging Capacity and Antioxidant Activity of the E Vitamer Fraction in Rice Bran. J Food Sci. 2006; 70(3):C208–C213
Rohman A, Riyanto S, Utari D. Antioxidant Activities, Total Phenolic and Flavonoid Contents of Ethyl Acetate Extract of Mengkudu (Morinda citrifolia, L) Fruit and Its Fractions. Indonesian Journal of Pharmacy. 2006; 0(0):136–142
Reynertson KA, Basile MJ, Kennelly EJ. Antioxidant Potential of Seven Myrtaceous Fruits. Ethnobotany Research and Applications. 2005; 3(0):025–036
Rabeta M, Nur Faraniza R. Total Phenolic Content and Ferric Reducing Antioxidant Power of the Leaves and Fruits of Garcinia atrovirdis and Cynometra cauliflora. Int Food Res J. 2013; 20(4):1691–1696
