AKTIVITAS SENYAWA FLAVANOID EKSTRAK ETANOL BUNGA KERSEN (Muntingia calabura L) SEBAGAI TABIR SURYA

Masdiana Tahir, Rahmawati Rahmawati, St Maryam, Putri Nurfauziah, Naura Nazhifah

Abstract


Chronic exposure to ultraviolet rays from the sun might result in oxidative stress, changes in the structure and composition of the skin. Sunscreen preparations are recommended to be used to prevent or minimize the harmful effects of UV rays on the skin. Sunscreen can be obtained from natural ingredients, one of which is the flower of cherry (Muntingia calabura L.). This study aims to identify the content of flavonoids and test the sunscreen activity of the ethanol extract of cherry flower (Muntingia calabura L.) in vitro using the UV-Vis spectrophotometric method based on the SPF value. Flavonoids are claimed to be capable to blocking ultraviolet (UV) light-induced radicals that have a protective effect against UV radiation, where the SPF value is a universal measure that describes the potency of a UV defense material. The findings of this study showed that the ethanol extract of cherry flowers positively contained flavonoid compounds including the flavonol, flavanone, and anthocyanidin groups. The results of the sunscreen activity test showed that the ethanol extract of cherry flowers had sunscreen activity at a concentration of 0.01% with an SPF value of 10.9 (moderate SPF), 0.05% with an SPF value of 41.6 (high SPF), 0,15% with an SPF value of 45.5 (high SPF). and 0.25% with an SPF value of 48.7 (high SPF). The higher the extract concentration, the higher the SPF value indicating the greater the activity as sunscreen.


Keywords


Cherry flowers; flavonoid, Muntigia calabura L; SPF; Sunscreen

References


Misnadiarly AS. Faktor-Faktor Yang Berpengaruh Terhadap Kerusakan Kulit. Cermin Dunia Kedokteran. 2006; 152:43–45

Susanti M, Dachriyanus, Putra DP. Aktivitas Perlindungan Sinar UV Kulit Buah Garcinia mangostana Linn Secara in Vitro. Pharmacon: Jurnal Farmasi Indonesia. 2012; 13(2):61–64

Stanfield JW. Sun Protectans : Enhancing Prodduct Functionality with Sunscreeens, in Schueeller, r. and Romanowski, p.Multifunctional Osmetic. New York : Marcel Dekker Inc. 2003

Pradika Y. Uji Aktivitas Tabir Surya Ekstrak Batang Pisang Ambon (Musa paradisiacal Var.Sapientum) (Disertasi). Yogyakarta: Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Kalijaga. 2016

Zahara M, Suryady. Kajian Morfologi Dan Review Fitokimia Tumbuhan Kersen (Muntingia calabura L). Pedagogik: Jurnal Ilmiah Pendidikan dan Pembelajaran . 2018; 5(2):69–74

Dutra EA, Oliveira DAG da C, Kedor-Hackmann ERM, Santoro MIRM. Determination of Sun Protection Factor (SPF) of Sunscreens by Ultraviolet Spectrophotometry. Revista Brasileira de Ciências Farmacêuticas. 2004; 40(3):381–385

Mbanga L et al. Determination of Sun Protection Factor (SPF) of Some Body Creams and Lotions Marketed in Kinshasa by Ultraviolet Spectrophotometry. IJARCS. 2014; 1(8):7–13

Ahmad AR, Juwita J, Ratulangi SAD. Penetapan Kadar Fenolik Dan Flavonoid Total Ekstrak Metanol Buah Dan Daun Patikala (Etlingera elatior (Jack) R.M.SM). Pharmaceutical Sciences and Research. 2015; 2(1):1–10

Markham KR. The Tehniques of Flavonoid Identification. Bandung: ITB. 1988

Zirconia A, Kurniasih N, Amalia V. Identifikasi Senyawa Flavonoid Dari Daun Kembang Bulan (Tithonia diversifolia) Dengan Metode Pereaksi Geser. al-Kimiya. 2015; 2(1):9–17

Rahayu S, Kurniasih N, Amalia V. Ekstraksi Dan Identifikasi Senyawa Flavonoid Dari Limbah Kulit Bawang Merah Sebagai Antioksidan Alami. al-Kimiya. 2015; 2(1):1–8

Malsawmtluangi C et al. Determination of Sun Protection Factor (SPF) Number of Some Aqueous Herbal Extracts. J Appl Pharm Sci. 2013; 3(9):150–151

Mansur JS, Breder MNR, Mansur MCA, Azulay RD. Determinação Do Fator De Proteção Solar Por Espectrofotometria. An Bras Dermatol Rio De Janeiro. 1986; 61:121–124

Puspitasari AD, Proyogo LS. Perbandingan Metode Ekstraksi Maserasi Dan Sokletasi Terhadap Kadar Fenolik Total Ekstrak Etanol Daun Kersen (Muntingia calabura). Jurnal Ilmiah Cendikia Eksakta. 2017; 2(1):16–13

Arikalang TG, Sudewi S, Rorong JA. Optimasi Dan Validasi Metode Analisis Dalam Penentuan Kandungan Total Fenolik Pada Ekstrak Daun Gedi Hijau (Abelmoschus manihot L.) Yang Diukur Dengan Spektrofotometer UV-VIS. PHARMACON. 2018; 7(3):14–21

Aminah A, Tomayahu N, Abidin Z. Penetapan Kadar Flavonoid Total Ekstrak Etanol Kulit Buah Alpukat (Persea americana Mill.) Dengan Metode Spektrofotometri UV-VIS. Jurnal Fitofarmaka Indonesia. 2017; 4(2):226–230

Ergina SN, Pursitasari ID. Uji Kualitatif Senyawa Metabolit Sekunder Pada Daun Palado (Agave angustifolia) Yang Diekstraksi Dengan Pelarut Air Dan Etanol. J Akad Kim. 2014; 3(3):165–172

Maryam S, Tahir M, Alifiah NI, Sari FF. Aktivitas Ekstrak BungaKersen (Muntigia calabura L.) Sebagai Antioksidan Dan Penghambat Enzim Xantin Oksidase Untuk Obat Asam Urat Secara In Vitro. Makassar: Penelitian Internal UMI, LP2S UMI. 2020

Nursakinah, Tahir M, Effendi N. Aktivitas Antioksidan Ekstrak Metanol Bunga Kersen (Muntigia calabura L.) Menggunakan Metode FRAP (Skripsi). Makassar: Fakultas Farmasi, Universitas Muslim Indonesia. 2018

Hogade MG, Basawaraj SP, Dhumal P. Comparative Sun Protection Factor Determination of Fresh Fruits Extract of Cucumber VS Marketed Cosmetic Formulation. Research Journal of Pharmaceutical. 2010; 1:55–59

Walters C et al. The Spectrophotometric Analysis and Modeling of Sunscreens. J Chem Educ. 1997; 74(1):99

Nisfah ZL, Syarief SH, Taufikurrohmah T. UJI Aktivitas Gabungan Nanogold-Nanoplatinum Sebagai Senyawa Tabir Surya Dalam KosmetiK. UNESA Journal of Chemistry . 2016; 5(2):77–82

Anderson K. Sun Proctection Is Easier than You Think. Bozeman: Montana State University. 2011

Widyawati E, Ayuningtyas ND, Pitarisa AP. Penentuan Nilai SPF Ekstrak dan Losio Tabir Surya Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Dengan Metode Spektrofotometri UV-VIS. Jurnal Riset Kefarmasian Indonesia. 2019; 1(3):189–202




DOI: https://doi.org/10.56711/jifa.v14i2.839

Refbacks

  • There are currently no refbacks.


Indexed by:

     

ISSN: 2085-4714 | e-ISSN: 2502-9444

Editor's Address:

Faculty of Pharmacy, Univeristas Muslim Indonesia
2nd Campus of UMI: Jl. Urip Sumoharjo km. 5 , Makassar, South Sulawesi, Indonesia

E-mail: jurnal.farmasi@umi.ac.id

View My Stats