Efek Pemberian Minyak Zaitun (Olive oil) Terhadap Perubahan Profil Lipid Pada Tikus putih (Rattus novergicus)

Rachmat Faisal Syamsu

Abstract


This research aims to know  the effects of olive oil  to changes profil lipid (total cholesterol, LDL, HDL, and triglycerides)  in the blood of the Rattus novergicus who were given a  high cholesterol diet. This research is experimental research methods laboratory with pre and post test control . Homogeneous data and normal data  next performed a test of paired t-Test and LSD test.  All test data using the 95% significance level (p = 0.05).  Conclusion of this research is the olive oil was able to lower the lipid profile, cholesterol 22,61%, LDL 38,48%, triglycerides 17.61% and increase the HDL 25.32%  in the blood of rats high cholesterol diet


References


Chesebro JH et all. Thrombolysis in myocardial infarction. (TIMI), 2006.

Okada T et all. Antibodies against heat shock protein 60 derived from Helicobacter pylori diagnostic implications in cardiovascular disease. Journal of Auitoimmunity 2007;29:106-15.

Anwar BT. Manfaat Diet pada PenanggulanganHiperkolesterolemia. Surakarta: Repository USU, 2006.

Sigit S dan Bijanti R. Kadar Kolesterol Darah pada Tikus Hiperkolesterolemia Setelah Pemberian Kombinasi Diet Telur dengan Asam Lemak Omega-3, Lesitin dan Vitamin E. Media Kedokteran Hewan 2006;(18)2.

Orey C. Khasiat Minyak Zaitun Ala Meditreania. Jakarta : Penerbit Hikmah (PT Mizan Publika), 2008.

Kris E et all. High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations.Am J Clin Nutr 2009;70:1009-15

Widyaningsih W, Mulyono dan Rosidi UE. Efek Ekstrak Etanol Belimbing Manis (Averrhoa carambola L) sebagai Penurun Kadar Kolesterol. Media Farmasi 2007;6:9-14.

Hendra et all .Pengaruh pemberian minyak zaitun terhadap kadar kolesterol total dalam darah tikus wistar jantan yang diberi diet hiperlipid. Indonesian journal 2001;62:45.

Sanderson P et all. Dietary fatty acids and the immune system. Cell Immunol 2005;164:240-7.

Gill JMR et all. Effects of dietary monounsaturated fatty acids on lipoprotein concentrations, compositions, andsubfraction distributions and on VLDL apolipoprotein B kinetics: dose-dependent effects on LDL. Am J Clin Nutr 2003;78:47-56.

Veni H et all. Pengaruh minyak zaitun terhadap kolesterol dan trigliserida pada subyek hiperkolesterolemia. Jurnal Kedokteran Unhas 2012.

Dewi Anggraeni .Manfaat minyak zaitun terhadap kadar LDL dalam darah tikus putih yang diberi diet hiperlipidemia. Jember : Patologi klinik Fakultas kedokteran gigi, 2011.

Hanna K. Manfaat minyak zaitun terhadap kadar Kolesterol Total dalam darah tikus putih jantan yang diberi diet hiperlipidemia. Surakarta : Studi Farmasi UNISMUH., 2012.

Marrugat J et all. Effect of differing phenolic content in dietary olive oils o lipid and LDL oxidation. Eur J Nutr 2006;43:140-7.

Merchant AT et all. Carbohydrate intake and HDL in a multiethnic population. Am J Clin Nutr 2007;85:225-30.

Cicerale S et all. Biological activities ofphenolic compounds present in virgin olive oil. Int J Mol Sci 2010;11:458-79.

http//depkes.go.id/resources/download/general/Hasil%20Riskesdas%202013.pdfdiakses 25 Februari 2016.

Lucock M. Nutrition and Genomics: Nutrition and the ascent of humankind. Jon Wiley & Sons, Inc 2007.P,46-9.

Darmanescu D et all. Experimental avaluation ofsome biochemicl parameters after administration offatty acids ethanolamides from extra virgin olive oil in rats. Farmacia 2010;58 (2).




DOI: https://doi.org/10.56711/jifa.v9i1.236

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ISSN: 2085-4714 | e-ISSN: 2502-9444

Editor's Address:

Faculty of Pharmacy, Univeristas Muslim Indonesia
2nd Campus of UMI: Jl. Urip Sumoharjo km. 5 , Makassar, South Sulawesi, Indonesia

E-mail: jurnal.farmasi@umi.ac.id

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