AKTIVITAS ANTIMIKROBA KOMBINASI EKSTRAK PROPOLIS Trigona sp DAN JAHE (Zingiber officinale ROSCOE) TERHADAP BAKTERI Salmonella thypimurium

Muhammad Fadhlullah Mursalim, Abdul Wahid Jamaluddin

Abstract


This study aims to find the antimicrobial activity of a combination of extract propolis Trigona sp and gingger (Zingiber officinale var ROSCOE) against Salmonella thypimurium. The test was carried out by the method of diffusion disc with propolis and ginger test material. The study was conducted with 10 groups treatment, namely the combination of K1 (1mL ginger (30%)), K2 (1mL ginger (30)% & 1mL propolis (1%)), K3 (Ginger 1 mL (30%) & propolis 1 mL (5% ), K4 (1mL ginger (15%)) K5 (1mL ginger (15%) & 1mL propolis (1%)), K6 (1mL ginger (15%) & 1 mL propolis (5%)), K7 (1 mL propolis 1 %), K8 (1 mL propolis 5%), negative control K9 (DMSO 10%), and K10 (positive control amoxicillin). The results showed that the combination extract of propolis and ginger on K3 had the highest inhibition area of Salmonella thypimurium 12.26 mm. This study proves that various combinations of concentrations of propolis and ginger extract have antibacterial activity against the growth of Salmonella typhimurium.


Keywords


Propolis Trigona sp, Zingiber officinale var ROSCOE, Salmonella typhimurium

References


Greenwood. Antibiotics Susceptibility (Sensitivity) Test, Antimicrobial and Chemotheraphy. United State of America: Mc Graw Hill Company. 1995.

Hanief S. Efektivitas Ekstrak Jahe ( Zingiber officinale ROSCOE) Terhadap Pertumbuhan Bakteri Streptococcus viridans. Jurnal Universitas Islam Negeri Syarif Hidayatullah. 2013. 1-61 p.

Hegazi AG, Abd El Hady FK. Chemical and biological studies of Egyptian propolis. In: International Symposium On Apitherapy. 1997.

Lofty M. Biological activity of bee propolis in health and disease. Asian Pacific Journal of Cancer Prevention. 2006;Vol 7:22-31.

Sabir A. Aktivitas antibakteri flavonoid propolis Trigona sp terhadap bakteri Streptococcus mutans (In Vitro). Maj Ked Gigi. 2005;38(3):135–41.

Singh G, Kapoor IP, Singh P, de Heluani CS, de Lampasona MP, Catalan CA. Chemistry, antioxidant and antimicrobial investigations on essential oil and oleoresins of Zingiber officinale. Food Chem Toxicol. 2008;46(10):3295-302.

Novilla A. Aktivitas antibakteri ekstrak propolis Apis mellifera terhadap pertumbuhan Methicillin-Resistant Staphylococcus aureus (MRSA) secara in vitro. Jurnal Kesehatan Kartika Stikes A. Yani. 2010; 9-16.

Nursal W, Sri dan Wilda S. Bioaktifitas ekstrak jahe (Zingiber officinale Roxb.) dalam menghambat pertumbuhan koloni bakteri Escherichia coli dan Bacillus subtilis. Jurnal Biogenesis, 2006;2 (2): 64-66.

Madigan MT, Martinko JM, Parker J. Brock Biology of Microorganisms Tenth Edition. USA: Prentice Hall Inc, 2003.

Mulyani S. Komponen dan Anti-bakteri dari Fraksi Kristal Minyak Zingiber zerumbet. Majalah Farmasi Indonesia, 2010;21(3):178-184.

Prasetyorini, Hasan AEZ, Siregar R. Penerapan teknologi nanopartikel propolis Trigona spp asal Bogor sebagai antibakteri Eschericia coli secara in vitro. Ekologia, 2011;11(1):36-43.

Tabbu. Penyakit ayam dan penanggulangannya volume 1. Yogyakarta : Penerbit Kanisius, 2000.

Takaisi-Kikuni NB, Schilcher H. Electron microscopic and microcalorimetric investigations of the possible mechanism of the antibacterial action of a defined propolis provenance. Planta Med. 1994;60(3):222-7.




DOI: https://doi.org/10.56711/jifa.v11i1.471

Refbacks

  • There are currently no refbacks.


Indexed by:

     

ISSN: 2085-4714 | e-ISSN: 2502-9444

Editor's Address:

Faculty of Pharmacy, Univeristas Muslim Indonesia
2nd Campus of UMI: Jl. Urip Sumoharjo km. 5 , Makassar, South Sulawesi, Indonesia

E-mail: jurnal.farmasi@umi.ac.id

View My Stats