PENGARUH KOMPOSISI HERBAL DALAM MINUMAN TEH HIJAU GAMBUNG HERBAL TERHADAP HAMBATAN α-GLUKOSIDASE

Megawati Megawati, Hani Mulyani, Minarti Minarti, Teni Ernawati, Akhmad Darmawan

Sari


The aim of this study is to make a formula of green tea that is enriched by other herbs. Green tea drinks are made using the basic ingredients of gambung (THG) green tea enriched with sapodilla leaves (Manilkara zapota (Aw) bay leaves (Syzygium polyanthum (Am), Artocarpus communis (Un) breadfruit leaves, and cinnamon leaves (Cinnamomum verum (K)). The composition of gambung herbal green tea is made by reference to the antidiabetic activity of each herb. All the samples were tested for inhibition of α-glucosidase enzymes and toxicity using the lethality test method for brine shrimp. All samples showed good inhibition of the α-glucosidase enzyme barriers of gamboeng green tea (THG) 82.05%, sapodilla leaves (Aw) 97.81%, breadfruit leaves (Un) 73.34%, bay leaves (Am) 93.80%, cinnamon leaves (K) 91.24 %. The inhibition value of α-glucoside enzymes in the formulation of gamboeng herbal green tea drinks: 96.203% (GKUn) is higher when compared to the GKAm formula (94.78%) and GKAw (62.487%).


Kata Kunci


α-glukosidase, teh hijau gambung,brine shrimp lethality

Teks Lengkap:

Fulltext PDF

Referensi


Ajisaka. Teh Dahsyat Khasiatnya, VI-VIII, Stomata. Surabaya: 2012. hal 1 dan 28.

Johnson R, Bryant S, Alyson L, and Huntley. Green Tea and Green Tea Catechin Extracts: An overview of the clinical evidence. Maturitas. 2012;73:280–287.

Armoskaite V, Ramanauskiene K, Maruska A, Razukas A, Dagilyte A, Baranauskas A and Briedis V. The analysis of quality and antioxidant activity of green tea extracts. Journal of Medicinal Plants Research. 2011;5(5): 811-816.

Sutarna TH, Ngadeni A dan Anggiani R. Formulasi sediaan Masker Gel dari ekstrak etanol daun teh hijau (Camelia Sinensis L dan madu hitam (Apidorsata) sebagai antioksidan. Jurnal Ilmia Farmasi. 2013;1(1).

Rohdiana D. Keunggulan Polifenol teh. Food Review. 2012;7(7):44-47.

Brannon C. Green Tea: New benefits from an Old favorite Nutrition Dimention Inc., 2012. www.nutritiondimention.com. DOI=10.1.1.529.2116&rep=rep1&type=pdf

Alipoor B and Rad AH. A Review On The Therapeutical Effects Of Tea. Asian Journal of Clinical Nutrition. 2012;4:1–15.

Jayasekera S, Kaur L, Molan AL, Garg ML, Moughan PJ. Effects of season and plantation on phenolic content of unfermented and fermented Sri Lankan tea. Food Chem. 2014;152:546–551.

Lotulung PDN, Fajriah S, Sundowo A and Filaila E. Anti diabetic Flavanone Compound From The Leaves Of Artocarpus communis. Indosian Journal of Chemistry.2009;9(3):466-469.

Sakka L. Uji Efek Anti diare Seduhan KayuManis (Cinnamomum zeylanicum BI.) pada Mencit Jantan (Mus musculus). Journal of Pharmaceutical Science and Herbal Technology. 2016;1(1):19-22.

Bahriul P, Rahman N dan Diah AWM. Antioxidant Activity Test of Bay Leave (Syzygium polyanthum) Extract Using 1,1-diphenyl-2-picrilhidrazyl. J. Akad. Kim.2014; 3(3): 143-149.

Rahman S dan Wati A. Uji Efek Hipoglikemik Ekstrak Etanol Buah Sawo Manila (Manilkara zapota) Pada Mencit Jantan Yang Dinduksi Aloksan. As-Syifaa.2016;08(01):76-81.

Dewi RT, Darmawan A, Mulyani H, Lotulung PDN, Minarti and Megawati. α-Glucosidase Inhibitory Effect Of Sulochrin From Aspergillus and Its brominated Derivatives. Malaysia Journal of Science. 2018;37(1):70-81.

Megawati, Saepudin E, Hanafi M, Darmawan A and Lotulung PDN. Identification and Bioactivity Studies of Flavonoid Compounds from Macaranga hispida (Blume) Mull. Arg. Makara Jounal. Sci. 2015;19(3):96-100.

Tadera K, Minami Y, Takamatsu K and Matsuoka. Inhibition of α-Glukosidase and α-Amylase by Flavonoids. J Nutr Sci Vitaminol. 2006;52:149-153.

Yashin A, Yashin Y and Nemzer B. Determination of Antioxidant Activity in Tea Extracts, and Their Total Antioxidant. Content. American Journal of Biomedical Sciences. 2011;3(4):322-335.


Refbacks

  • Saat ini tidak ada refbacks.


View My Stats